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  • Open Targets Platform
  • Getting started
  • Target
    • Tractability
    • Safety
    • Chemical probes & TEPs
    • Baseline expression
    • Molecular interactions
    • Core Gene Essentiality
    • Pharmacogenetics
  • Disease or Phenotype
    • Clinical signs and symptoms
  • 🆕Variant
  • 🆕Study
  • Drug
    • Clinical Precedence
    • Pharmacovigilance
    • Pharmacogenetics
  • 🆕Credible Set
  • Target–disease evidence
  • Target–disease associations
  • 🆕GWAS & functional genomics
    • Data sources
    • Fine-mapping
    • Colocalisation
    • Locus-to-Gene (L2G)
    • Gentropy
  • Bibliography
  • Web interface
    • Associations on the Fly
    • Target Prioritisation
    • Evidence pages
    • Entity profile pages
  • Data and code access
    • Download datasets
    • Google BigQuery
    • GraphQL API
    • 🆕Platform infrastructure
    • 🆕Data pipeline
  • 🆕FAQs
  • Release notes
  • Citation
  • Licence
    • Terms of use
  • Partner Preview Platform
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Open Targets Platform

NextGetting started

Last updated 2 months ago

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Welcome!

The is a comprehensive tool that supports systematic identification and prioritisation of potential therapeutic drug targets.

By integrating publicly available datasets including data generated by the , the Platform builds and scores target-disease associations to assist in drug target identification and prioritisation. It also integrates relevant annotation information about targets, diseases/phenotypes, drugs, variants, studies, and credible sets as well as their most relevant relationships.

The Platform is a freely available resource that is actively maintained with quarterly updates. Our through an intuitive web user interface, an API, and data downloads. Likewise, our pipeline and infrastructure codebases are open-source and can be used to create a self-hosted private instance of the Platform with custom data. For more information, please review our and, if you use our data and/or pipelines, please cite .

Check out to learn more about the Platform and the Open Targets research programme.

You can also join the and follow us on:

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For additional help with the Open Targets Platform, or to report bugs, data issues, or submit a feature request, please post on the , using the relevant categories and tags. If the request you would like to make has already been posted, please like the post to indicate you would like this to be prioritised.

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