Release notes
22 February 2023
In addition to regular updates from our data providers, we have a number of new features in this release:
New evidence for target-disease associations
- Additional data for metabolic biomarkers added to our Gene Burden widget
- QTL-based direction of effect included in evidence from Open Targets Genetics
Improved target annotation data
- Integration of Target safety evidence from AOPWiki
- New data from Probes and Drugs’ 04.2022 release
Literature updates
- Preprints and patents now included in our bibliography
Development updates
- Redesigned search
- Provenance metadata
Check out the 23.02 release blog post for more information on the new features and datasets introduced in this release.
- 62,678 targets
- 24,713 diseases and phenotypes
- 12,854 drugs and compounds
- 10,446,771 evidence strings
- 6,656,559 target-disease associations
Visit the Open Targets Community 23.02 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
24 November 2022
In addition to continuous updates from our data providers, we have introduced the following new features:
- Gene burden data for Parkinson’s disease
- Updated classifications for clinical trial stop reasons
- Variant functional consequences, available to browse in the Gene2Phenotype and Orphanet widgets
- Other improvements and bug fixes
Check out the 22.11 release blog post for more information on the new features and datasets introduced in this release.
- 62,678 targets
- 22,274 diseases and phenotypes
- 12,854 drugs and compounds
- 14,611,717 evidence strings
- 6,960,486 target-disease associations
Visit the Open Targets Community 22.11 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
29 September 2022
New data, in particular:
- Open Targets Genetics
- Genomics England PanelApp
- Gene burden
- Probes and drugs
- New data integrity file, in line with FAIR principles
Check out the 22.09 release blog post for more information on the new features and datasets introduced in this release.
- 61,888 targets
- 20,931 diseases and phenotypes
- 12,854 drugs and compounds
- 14,229,684 evidence strings
- 7,003,171 target-disease associations
Visit the Open Targets Community 22.09 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
24 June 2022
- New data: five additional gene burden analyses from Genebass
- New feature: new visualisation of subcellular locations of targets now available to users
- New ontology term: “medical procedure”
Check out the 22.06 release blog post for more information on the new features and datasets introduced in this release.
- 61,524 targets
- 23,074 diseases and phenotypes
- 12,854 drugs and compounds
- 14,455,104 evidence strings
- 7,247,865 target-disease associations
Visit the Open Targets Community 22.06 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
28 April 2022
- New datasource: gene burden analyses from Regeneron and the AstraZeneca
- Integration of structural variants from ClinVar
- Additional information from DailyMed drug label text-mining
- NLP classification of why clinical trials stopped
- New data: Gene2phenotype cardiac panel
Check out the 22.04 release blog post for more information on the new features and datasets introduced in this release.
- 61,524 targets
- 18,520 diseases and phenotypes
- 12,854 drugs and compounds
- 13,829,174 evidence strings
- 7,541,360 target-disease associations
Visit the Open Targets Community 22.04 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
28 February 2022
- Gene2Phenotype terminology updated in line with the Gene Curation Coalition (GenCC)
- Data updates from a range of providers including Open Targets Genetics and ChEMBL
Check out the 22.02 release blog post for more information on the new features and datasets introduced in this release.
- 61,524 targets
- 18,468 diseases and phenotypes
- 12,594 drugs and compounds
- 10,880,832 evidence strings
- 7,980,448 target-disease associations
Visit the Open Targets Community 22.02 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
29 November 2021
- New Cancer Biomarkers evidence data from the Cancer Genome Interpreter
- Updated genetic association evidence from Open Targets Genetics
- Embedded GraphQL API playground for each data table and query
Check out the 21.11 release blog post for more information on the new features and datasets introduced in this release.
- 60,636 targets
- 18,706 diseases and phenotypes
- 12,594 drugs and compounds
- 10,481,189 evidence strings
- 7,787,231 target-disease associations
Visit the Open Targets Community 21.11 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
30 September 2021
- Integration of Genetic Constraint data from gnomAD and new Chemical Probes data from Probes & Drugs database
- Data updates from EFO, ChEMBL, and Mouse Genome Informatics
- Other improvements and bug fixes
Check out our 21.09 release blog post for more information on the new features and datasets introduced in this release.
- 60,636 targets
- 18,663 diseases and phenotypes
- 12,594 drugs and compounds
- 11,071,233 evidence strings
- 7,927,820 target-disease associations
Visit the Open Targets Community 21.09 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.
30 June 2021
- Updated Open Targets Genetics Portal evidence, which included the integration of FinnGen biobank data (R5) and new GWAS Catalog studies
- Integration of gene-disease data from Orphanet
- Improvements to the user interface (e.g. datatype chips on evidence page)
- Bug fixes (e.g. users can download Known Drugs table, association scores in datasets match values returned by API)
Check out our 21.06 release blog post for more information on the new features and datasets introduced in this release.
- 60,606 targets
- 18,507 diseases and phenotypes
- 13,185 drugs and compounds
- 13,267,236 evidence strings
- 9,216,710 target-disease associations
Visit the Open Targets Community for more data metrics for this release, including a per datasource breakdown of evidence strings.
For release notes for previous releases, check out the Open Targets Community News & Announcement section.
Last modified 25d ago