Release notes

22.04

Release date

28 April 2022

Highlights

  • New datasource: gene burden analyses from Regeneron and the AstraZeneca
  • Integration of structural variants from ClinVar
  • Additional information from DailyMed drug label text-mining
  • NLP classification of why clinical trials stopped
  • New data: Gene2phenotype cardiac panel
Check out the 22.04 release blog post for more information on the new features and datasets introduced in this release.

Overall data metrics

  • 61,524 targets
  • 18,520 diseases and phenotypes
  • 12,854 drugs and compounds
  • 13,829,174 evidence strings
  • 7,541,360 target-disease associations
Visit the Open Targets Community 22.04 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.

22.02

Release date

28 February 2022

Highlights

  • Gene2Phenotype terminology updated in line with the Gene Curation Coalition (GenCC)
  • Data updates from a range of providers including Open Targets Genetics and ChEMBL
Check out the 22.02 release blog post for more information on the new features and datasets introduced in this release.

Overall data metrics

  • 61,524 targets
  • 18,468 diseases and phenotypes
  • 12,594 drugs and compounds
  • 10,880,832 evidence strings
  • 7,980,448 target-disease associations
Visit the Open Targets Community 22.02 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.

21.11

Release date

29 November 2021

Highlights

  • New Cancer Biomarkers evidence data from the Cancer Genome Interpreter
  • Updated genetic association evidence from Open Targets Genetics
  • Embedded GraphQL API playground for each data table and query
Check out the 21.11 release blog post for more information on the new features and datasets introduced in this release.

Overall data metrics

  • 60,636 targets
  • 18,706 diseases and phenotypes
  • 12,594 drugs and compounds
  • 10,481,189 evidence strings
  • 7,787,231 target-disease associations
Visit the Open Targets Community 21.11 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.

21.09

Release date

30 September 2021

Highlights

  • Integration of new PROTAC tractability data from Schneider et al. (2021)
  • Integration of Genetic Constraint data from gnomAD and new Chemical Probes data from Probes & Drugs database
  • Data updates from EFO, ChEMBL, and Mouse Genome Informatics
  • Other improvements and bug fixes
Check out our 21.09 release blog post for more information on the new features and datasets introduced in this release.

Overall data metrics

  • 60,636 targets
  • 18,663 diseases and phenotypes
  • 12,594 drugs and compounds
  • 11,071,233 evidence strings
  • 7,927,820 target-disease associations
Visit the Open Targets Community 21.09 release thread for more data metrics for this release, including a per datasource breakdown of evidence strings.

21.06

Release date

30 June 2021

Highlights

  • Updated Open Targets Genetics Portal evidence, which included the integration of FinnGen biobank data (R5) and new GWAS Catalog studies
  • Integration of gene-disease data from Orphanet
  • Improvements to the user interface (e.g. datatype chips on evidence page)
  • Bug fixes (e.g. users can download Known Drugs table, association scores in datasets match values returned by API)
Check out our 21.06 release blog post for more information on the new features and datasets introduced in this release.

Overall data metrics

  • 60,606 targets
  • 18,507 diseases and phenotypes
  • 13,185 drugs and compounds
  • 13,267,236 evidence strings
  • 9,216,710 target-disease associations
Visit the Open Targets Community for more data metrics for this release, including a per datasource breakdown of evidence strings.

Archive

For release notes for previous releases, please contact [email protected] or check out the Open Targets Community News & Announcement section.
Last modified 25d ago