> For the complete documentation index, see [llms.txt](https://platform-docs.opentargets.org/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://platform-docs.opentargets.org/gentropy.md).

# GWAS & functional genomics

The Platform is built upon a significant effort to analyse genome-wide associations studies and interpret them in the context of functional genomics studies. This effort to inform target identification and prioritisation datasets leverages [gentropy](/gentropy/gentropy.md) a highly-scalable python framework for post-GWAS analysis.

A more detailed view on the data and methodology is available in:

* [Data sources](/gentropy/data-sources.md) used to ingest variant annotation, GWAS and functional genomics information. 
* [Fine-mapping](/gentropy/fine-mapping.md) pipelines to identify likely causal variants in GWAS-significant signals in different sources.
* [Enhancer-to-gene](/gentropy/enhancer-to-gene-encode-re2g.md) dataset to connect variants to genes using rE2G model scores.
* [Colocalisation](/gentropy/colocalisation.md) performed on overlapping GWAS and molQTL credible sets.
* [Locus-to-Gene](/gentropy/locus-to-gene-l2g.md) predictions to assess likely causal genes near identified credible sets.